ABSTRACT
Primary antiphopholipid syndrome (APS) is a disease producing vascular thrombus with antiphospholipid antibody without association with autoimmune diseases as systemic lupus erythematosus. Retinal vein occlusion is a rare vascular manifestation in primary APS. We describe 2 cases of primary APS presenting with developing blurred vision. Each had central retinal vein occlusion and high titer of IgG anticardiolipin antibody.
Subject(s)
Adult , Humans , Male , Antibodies, Anticardiolipin/analysis , Antiphospholipid Syndrome/complications , Middle Aged , Retinal Vein Occlusion/etiologyABSTRACT
Dermatomyositis is a disorder of unknown etiology characterized by an inflammatory myopathy involving striated skeletal muscle and associated characteristic skin lesions.The relationship between dermatomyositis and malignant tumor remains controversial,but we must be concerned about evaluation of suspected malignancy in a patient with dermatomyositis. We present a case of dermatomyositis associated with lung cancer.A 51-year-old male has suffered proximal muscle weakness and facial erythema for 2 months.Pathologic results showed adenocarcinoma and pneumonectomy of the left lung was performed.Myositis resolved completely after removing the malignant mass.Few cases of malignant tumors associated with dermatomyositis were reported in Korea,but dermatomyositis associated with non-small cell lung cancer and complete remission of myositis after the tumor resection has not been reported previously.
Subject(s)
Humans , Male , Middle Aged , Adenocarcinoma , Carcinoma, Non-Small-Cell Lung , Dermatomyositis , Erythema , Lung Neoplasms , Lung , Muscle Weakness , Muscle, Skeletal , Myositis , Pneumonectomy , SkinABSTRACT
Hereditary hemorrhagic telangiectasia (HHT), also known as Rendu-Osler-Weber disease, is a rare autosomal dominant disorder characterized by hemorrhage from nasal, mucocutaneous and gastrointestinal telangiectasia, in addition to vascular anomalies in other organs, particularly in the pulmonary, hepatic and cerebral circulations. The most common clinical manifestations are epistaxis and gastrointestinal bleeding. Endoscopic band ligation is effective for non-variceal, non-ulcer bleeding. It has the advantage of ease of use and is relatively inexpensive. We report a case of endoscopic band ligation therapy for gastric bleeding in patient with Rendu-Osler-Weber disease.
Subject(s)
Humans , Epistaxis , Hemorrhage , Ligation , Telangiectasia, Hereditary Hemorrhagic , TelangiectasisABSTRACT
A 45-year-old man presented with muscle pain, skin nodules and persistent hypereosinophilia over a period of 4 months. Laboratory data excluded the diagnosis of trichinosis or any other parasite infection. The patient's course of the disease over the 9 months was compatible with idiopathic hypereosinophilic syndrome. In a muscle biopsy, eosinophilic and lymphoplasma cells are predominantly infiltrated. Authors report a case of rhabdomyolysis due to eosinophilic polymyositis in idiopathic hypereosinophilic syndrome.
Subject(s)
Male , Humans , BiopsyABSTRACT
Spinal epidural emphysema is rare, and only a few cases have ever been reported. A 18 year-old man was admitted for neck and chest pain for 3 days. Before admission he experienced rhinorrhea and severe cough. Physical examination revealed wheezing on whole lung field and subcutaneous emphysema over the upper portion of the chest and neck. Chest radiograph showed pneumomediastinum ajdn subcutaneous emphysema in the neck and chest CT images demonstrate a free air in the prevertebral fascia. With coservative management, the patient's condition and the pneumomediastinum improved. The patient was discharged to home on the fourteenth day.
Subject(s)
Humans , Asthma , Chest Pain , Cough , Emphysema , Fascia , Lung , Mediastinal Emphysema , Neck , Physical Examination , Radiography, Thoracic , Respiratory Sounds , Subcutaneous Emphysema , Thorax , Tomography, X-Ray ComputedABSTRACT
Behcet's disease is a multisystemic, chronic inflammatory disease with a triad of symptoms including oral ulcers, genital ulcers, and inflammatory ocular lesions. While intestinal Behcet's disease commonly affects the ileocecal region, esophageal ulceration with odynophagia is very uncommon. A 38-year-old male patient was admitted due to odynophagia, a postprandial epigastric burning sensation, and right lower quadrant abdominal pain. He had a history of recurrent oral and genital ulcerations. An esophagogastroduodenoscopy revealed relatively well demarcated ulcerative lesions with mucosal nodularities on the mid to distal esophagus which was suspected to be esophageal cancer. But repeated biopsies showed lymphocytic and plasma cell infiltrations on the lamina propria. A colonoscopy revealed a well demarcated, deep ulcerative lesion with stenotic narrowing in the ileocecal valve. The diagnosis of intestinal Behcet's disease with an esophageal ulcer was made on the basis of clinical and pathological findings. The patient was treated with steroids and sulfasalazine and the response was favorable.
Subject(s)
Adult , Humans , Male , Abdominal Pain , Biopsy , Burns , Colonoscopy , Diagnosis , Endoscopy, Digestive System , Esophageal Neoplasms , Esophagus , Ileocecal Valve , Mucous Membrane , Oral Ulcer , Plasma Cells , Sensation , Steroids , Sulfasalazine , UlcerABSTRACT
Distal renal tubular acidosis is classified into primary and secondary. Sjogren Syndrome is the most common cause of secondary distal RTA. We experienced a 51 year-old female patient who had many manifestations of primary Sjogren syndrome which showes Distal renal tubular acidosis, acute pancreatitis, acute renal failure, possibly nephrogenic diabetes insipidus, but We found other atypical findings including ANA negative serology, high anion gap metabo1ic acidosis.
Subject(s)
Female , Humans , Middle Aged , Acid-Base Equilibrium , Acidosis , Acidosis, Renal Tubular , Acute Kidney Injury , Diabetes Insipidus, Nephrogenic , Pancreatitis , Sjogren's SyndromeABSTRACT
A 34-year-old male who has recieved regular hemodialysis three times a week for 2years due to chronic renal failure was admitted due to chest pain. Chest x-ray and computed tomography showed large sized anterior mediastinal mass compressing heart and great vessels posteriorly. Open lung biopsy was performed and the result was spindle cell type thymoma. We recommanded surgical resection but he refused and discharged. After 8 months, we observed marked regression of the thymoma without any other treatment. We report a case of spontaneous regression of thymoma in patient with chronic renal failure during regular hemodialysis.
Subject(s)
Adult , Humans , Male , Biopsy , Chest Pain , Heart , Kidney Failure, Chronic , Lung , Renal Dialysis , Thorax , ThymomaABSTRACT
The primary pulmonary lymphomas are uncommon, accounting for 0.5% of primary lung tumor and 0.4% of all malignant lymphomas. The majority of primary pulmonary lymphomas are of B-cell originating from bronchus associated lymphoid tissue(BALT). Angiocentric lymphoma is a rare type of primary pulmonary lymphomas characterized by polymorphic lymphoid infiltrates, which make it even more difficult to differentiate from benign infiltration. The radiographic findings are variable, depending on the stage of evolution of the disease. The prognosis of angiocentric lymphoma is poor, nearly two-thirds of the patients with grade 2 or 3 angiocentic lymphomas were died within a year of diagnosis. We report a case of primary pulmonary angiocentric lymphoma manifested as a mass of right lower lobe.